It is estimated that there are currently 640,000 survivors of polio in the United States. Studies suggest that 20% to 40 % of individuals who have recovered from APP go on to develop PPS; thus, there may be as many as 128,000 to 256,000 individuals with PPS in the United States. PPS is equally prevalent in male and female polio survivors. Post-polio syndrome (PPS) typically develops 30 to 40 years after recovery from polio, but intervals as short as 8 years and as long as 71 years have been documented.

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